Review of the Highest-Rated CPAP Machines for 2022


While all CPAP machines perform the same task, selecting the one that best matches your personal needs and preferences can be stressful. To ease this process, we handpicked a few models according to their performance in all the important aspects. This 2022 CPAP machine buying guide details all you need to know about the highest rated CPAP machines that will help achieve exceptionally high levels of effectiveness in treating obstructive sleep apnea (OSA).

ResMed AirMini AutoSet

The ResMed AirMini AutoSet is one of the highest rated CPAP machines. Its miniature size and light weight make it one of the preferable travel companions. Many frequent travelers prefer the AirMini, since it fits in the palm. Users also enjoy convenient control and waterless humidification, which is much better than tanked humidification. However, the AirMini Autoset is not optimized for home use since its small size makes it louder than one would prefer when at home.

Human Design Medical Z2 Auto Travel CPAP Machine

The Z2 has a good reputation for its portability, extended battery life, and waterless humidification system. Unlike the ResMed AirMini AutoSet, this CPAP machine is quieter, making it a good option for use in transit and at home.

ResMed AirSense 11 AutoSet

The new AirSense 11 is an upgrade of the AirSense 10. Stores that sell CPAP machinesrecommend it to first-time users since it incorporates great tools optimized for people beginning their CPAP therapy journey. The AirSense 11 has a single physical button for starting and stopping therapy, touchscreen controls, automatic software updates, a personalized experience, and improved security and comfort features.

3B Medical Luna II Auto CPAP Machine

The Luna II Auto ranks among the highest rated CPAP machines due to its affordability. Unlike you would expect, this CPAP machine achieves the effectiveness of other higher-priced models, owing to its high-level features. It has ramp functionality, ultra-quiet operation, a friendly user interface, and a therapy data tracking feature. Stores that sell CPAP machines recommend it for its reliability since it uses an auto-titration algorithm that allows you more time to fall asleep than most machines do.


These CPAP machines have different features that are optimized for different people’s lifestyles. We hope our list has provided some valuable insight that will help you select the one that best serves your needs. We mainly recommend the ResMed AirSense 11 AutoSet as the highest rated cpap machines since it is excellent for home and transit needs. We also recommend the 3B Medical Luna II Auto CPAP Machine if you seek a cheap but excellent choice.

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